Cell mediated immunity is the result of T lymphocytes or T-cells. T cells are produced in the thymus gland, they respond to both pathogen cells but also the body’s own cells altered by viruses or cancer and to transplanted tissues. T-cells will only respond to the presence of an antigen.


  1. The pathogen enters the body after passing through the bodies physical barriers (e.g. skin)
  2. Some of the pathogens are engulfed by the phagocytosis phagocytes in phagocytosis and gets into the body’s tissues
  3. Phagocytes break the pathogen down using enzyme and presents its antigens on the phagocytes cell membrane for the T cells
  4. The receptors on the T helper cells then takes the antigen from the phagocyte
  5. This activates the T cells to clone through mitosis to produce
  • Memory cells: cells which remain in the body that lay dormant for the most part until the same pathogen’s
    antigens are found again the in the body in which the memory cells are able to reactivate
    and produce the antibodies that worked last time. Memory cells are specific to the one type of pathogen.
  • Cytotoxic T cell (Tc cells) which can make holes in the cell membrane of the pathogen causing it to break down
  • Stimulates the phagocytes to engulf the pathogens
  • Stimulate B-cells to divide